Tay-Sachs disease is caused by a recessive allele. About 1 in 3,600 live births is affected with Tay-Sachs disease. What is the allelic frequency of each allele? In a population of 1,000 people, about how many will be heterozygous carriers of the Tay-Sachs allele?
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Since Tay-Sachs disease affects 1 in 3,600 live births, we can assume that the disease is rare enough that the frequency of the recessive allele is small. Therefore, we can simplify the equation to: 2pq ≈ 1 Solving for q, we get: q ≈ 1/60 Therefore, the Show more…
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