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Hi there.
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Today we're talking about antibody diversity.
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We have three different things we're talking about.
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The first one being somatic recombination.
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So let's get read, underline it, and talk about it.
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So somatic recombination.
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It refers to the process of generating antibody and tcr diversity.
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And it's unique among mammals.
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What it does is basically it takes, it's a type of gene rearrangement by which shells of the adaptive immune system physically cut out small parts of dna or regions of dna and then paste the remaining piece of the dna back together in an air prone way.
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It helps in creating antibody diversity because it's doing this on the end of the antibody, as you know, antibodies, we're thinking about like a y -shaped thing, and basically it helps.
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Helps with making sure those ends are definitely not the same.
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The next step, let's work on junctional diversity.
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So let's use junctional diversity.
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That has something to do with junctions.
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I'm pretty sure.
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It includes the process of somatic recombination...