Which antibiotic interferes with the transport of peptidoglycan precursors across the cytoplasmic membrane: * Bacitracin Streptomycin Fluoroquinolones Penicillin How many different bacteria species do you carry with you everyday? * 10 A few hundreds A few thousands A few millions A few billions Among the following locations, which one is the most likely to be sterile? * Your kitchen Your bathroom A surgery room A hot-dog from the Yankee Stadium The womb of a pregnant mouse Which antibiotics blocking protein synthesis and among the first drugs to fight tuberculosis was discovered by a future Brooklyn College faculty and his PhD advisor? * Vancomycin Rapamycin Ritalin Bacitracin Streptomycin
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The antibiotic that interferes with the transport of peptidoglycan precursors across the cytoplasmic membrane is Bacitracin. Show more…
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Which of the following are NOT ideal antibacterial drug targets? (select ALL that apply) a. Peptidoglycan b. 60S ribosome c. Cell membrane d. DNA/RNA e. 50S ribosome f. Chitin g. Folic acid synthesis Which of the following antibiotics target bacterial cell walls? (select all that apply) a. Penicillin b. Tetracycline c. Macrolide d. Cephalosporin e. Metronidazole f. Vancomycin g. Trimethoprim h. Chloramphenicol i. Rifampin Which of the following antibiotics target bacterial protein synthesis? (select all that apply) a. Penicillin b. Tetracycline c. Macrolide d. Cephalosporin e. Metronidazole f. Vancomycin g. Trimethoprim h. Chloramphenicol i. Rifampin
Adi S.
Antimicrobial Drug Mode of action Penicillin Affects peptidoglycan to cause cell wall damage and lysis Chloramphenicol Inhibits protein synthesis by binding to 70S ribosomes Binds to ergosterol to affect cell membrane Amphotericin B Quinines Causes buildup of toxic free radicals in parasite's cells Oseltamivir Prevents viral budding Refer to the table given above to answer the following: A) Which of the drugs given in the table above could be used to treat yeast infection with selective toxicity? B) Explain why your choice of antimicrobials would be selectively toxic: C) Explain why you eliminated all the other choices of antimicrobials.
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1. What is an antibiotic? 2. What are the uses of antibiotics? 3. Fill out the following table: Antibiotic Target cell Molecular target Next step that will not be possible Tetracycline Chloramphenicol Puromycin Erythromycin Fucidic acid Ricin 4. 40% of all known antibiotics target the translational machinery. What are the other antibiotics targeting? 5. Why are antibiotic-resistant bacteria such a threat to our communities?
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