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Chapter 9 Review: Molecular Genetics Learning Objectives and Application Questions Learning objectives are identified for you to review your understanding of this topic. You are advised to reflect carefully on these objectives and check your own understanding to see if you have understood these essential concepts from this week's reading. ANSWER THOROUGHLY all the application questions associated with each objective IN YOUR OWN WORDS. Learning Objective I: Describe the structure of DNA (p. 202, 203) Application question #1 – Match the following scientists with their corresponding discovery. Note: one item on the right will be used more than once. 1.Rosalind Franklin A. Credited with discovering the Double Helix model of DNA 2.Erwin Chargaff B. Provided the basis for pairing of complimentary DNA bases 3.James Watson C. Used X-ray crystallography to discover DNA's helical shape 4.Francis Crick 5.Maurice Wilkins Application question#2 – Write in the missing words in the statement below. The building blocks of a DNA molecule are called ¹ _______. Each one of these building blocks consists of the 5-carbon sugar ² _, a ³ _, and one ? _base. There are four bases in DNA called ? _, _, _, and _. Application Question #3 – There is a strict rule specifying how DNA bases in the double helix model should pair. This rule states that the base Adenine must always pair with ¹ _, and ² _, must always pair with ³ _. Learning Objective II. Explain the semi-conservative process of DNA replication and repair in eukaryotes (p. 206, 207). Application Question #4 – In your own words (do not copy + paste an answer from any source), describe the meaning of semi-conservative replication. Application question #5 – Use the pairing rules of semi-conservative replication to copy (replicate) the single strand of DNA provided below: DNA Template: A T T C G A T C G A C G DNA Replica: ___________

Chapter 9 Review: Molecular Genetics
Learning Objectives and Application Questions
Learning objectives are identified for you to review your understanding of this topic. You are
advised to reflect carefully on these objectives and check your own understanding to see if
you have understood these essential concepts from this week's reading.
ANSWER THOROUGHLY all the application questions associated with each objective IN YOUR
OWN WORDS.
Learning Objective I: Describe the structure of DNA (p. 202, 203)
Application question #1 – Match the following scientists with their corresponding discovery. Note:
one item on the right will be used more than once.
1.____Rosalind Franklin
A. Credited with discovering the Double Helix model of DNA
2.____Erwin Chargaff
B. Provided the basis for pairing of complimentary DNA bases
3.____James Watson
C. Used X-ray crystallography to discover DNA's helical shape
4.____Francis Crick
5.____Maurice Wilkins
Application question#2 – Write in the missing words in the statement below.
The building blocks of a DNA molecule are called ¹ _____________________. Each one of these building
blocks consists of the 5-carbon sugar ² _____________________, a ³ _____________________, and
one ? _____________________base. There are four bases in DNA called ? _____________________, _____________________,
_____________________, and _____________________.
Application Question #3 – There is a strict rule specifying how DNA bases in the double helix model
should pair. This rule states that the base Adenine must always pair with ¹ _____________________, and ² _____________________,
must always pair with ³ _____________________.
Learning Objective II. Explain the semi-conservative process of DNA replication and repair in eukaryotes
(p. 206, 207).
Application Question #4 – In your own words (do not copy + paste an answer from any source),
describe the meaning of semi-conservative replication.
Application question #5 – Use the pairing rules of semi-conservative replication to copy (replicate) the
single strand of DNA provided below:
DNA Template: A T T C G A T C G A C G
DNA Replica: _____________________

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